Cell and Molecular Biology

Paper Code: 
BOT 201
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
10.00
Unit I: 

Cell envelopes and organelles : Cell wall : structure, plasma membrane: structure, models and functions, structure and function of chloroplast, mitochondria, golgi bodies, endoplasmic reticulum, lysosomes, plasmodesmata, vacuoles, ribosomes, biogenesis of chloroplast and mitochondria. Ultrastructure of nucleus, nuclear membrane, nucleolus, nuclear pores.

10.00
Unit II: 

Chromosome Organization: Chromosome structure and packaging of DNA, specialized type of chromosome: Polytene and lampbrush chromosome, B chromosomes,  Heterochromatin and Euchromatin, Barr bodies.

8.00
Unit III: 

Cell Division: Amitosis, Mitosis, Meiosis, Cell cycle .

10.00
Unit IV: 

DNA-The Genetic Material: DNA structure, A, B and Z forms , replication, DNA damage and repair, DNA methylation, transposons , satellite and repetitive DNA, transcription of DNA, transcription factors, RNA processing, translation.

7.00
Unit V: 

RNA-The Genetic Material: RNA structure and its types- r RNA , mRNA , and tRNA. Biogenesis and structure of different types of RNA, RNA editing, nucleolus and ribosomal RNA genes.

Essential Readings: 
  1. Alberts, B; Bray, D; Lewis, J; Raff, M; Roberts,K and Watson, JD. 1999. Molecular Biology of the Cell. Garland Publishing Inc., New York.
  2. Buchanan, BB; Gruissem, W and Jones, RL. 2000. Biochemistry and Molecular Biology of Plants. American Society of Plant Physiologists. Maryland, USA.
  3. Powar,C.B. Cell Biology. Himalaya Publishing House, Mumbai.
  4. Introductory Cell Biology. Veer Bala Rastogi.
References: 
  1. De Robertis. Cell and Molecular Biology. Waverly International.
  2. Karp and Gerald. Cell and Molecular Biology: Concepts and Experiments (3rd edition). John Wiley & Sons.
  3. Kleinsmith, LJ and Kish, VM. 1995. Principles of Cell and Molecular Biology (2nd edition). Harper Collins College Publishers. New York, USA.
  4. Krishnamurthy, KV. 2000. Methods in Cell Wall Cytochemistry. CRC Press,Boca Raton; Florida.
  5. Lewin, B 2000. Genes VII. Oxford University Press, New York.
  6. Lodish, H; Berk, A; Zipursky, SL; Matsudiara, P; Baltimore, D and Darnell, J. 2000. Molecular Cell Biology (4th edition). WH Freeman & Co., New York.
  7. Rost, T et al. 1998. Plant Biology. Wordsworth Publishing Co. California, USA.
  8. Wolfe, SL. 1993. Molecular and Cellular Biology. Wordsworth Publishing Co. California, USA.
  9. Weil, JH. 2003. Molecular Insight in Plant Biology. Oxford & IBH Publishing Co. Pvt. Ltd.

 

Academic Year: