Cell and Molecular Biology

Paper Code: 
BOT 201
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
Objective: 

To study the molecular aspects of cell structure and functions in plant cell.

                            

 

9.00
Unit I: 
Cell envelopes and organelles

Cell wall: structure, plasma membrane:  structure, models and functions, structure and function of chloroplast, mitochondria, golgi bodies, endoplasmic reticulum, lysosomes, plasmodesmata, vacuoles, ribosomes, biogenesis of chloroplast and mitochondria. 

 

9.00
Unit II: 
Nuclear Organization

Ultrastructure of nucleus, nuclear membrane, nucleolus, nuclear

pores.Chromosome structure and packaging of DNA, specialized type of chromosome: Polytene and lampbrush chromosome, B chromosomes, Heterochromatin and Euchromatin, Barr bodies

 

9.00
Unit III: 
Cell Division

Amitosis, Mitosis, Meiosis.

Cell cycle: Phases of cell cycle, Cell cycle checkpoints, role of cyclins and cyclin dependent kinases.

 

9.00
Unit IV: 
DNA-The Genetic Material

A, B and Z forms; DNA damage and repair, DNA methylation; satellite and repetitive DNA, DNA replication, transcription and translation.

9.00
Unit V: 
RNA-The Genetic Material

 Biogenesis, structure and its types- rRNA, mRNA, and tRNA, RNA processing (splicing of m RNA, rRNA and tRNA), RNA editing and transposons.

 

Essential Readings: 

·         Alberts, B; Bray, D; Lewis, J; Raff, M; Roberts,K and Watson, JD. 1999. Molecular Biology of the Cell. Garland Publishing Inc., New York.

·         Buchanan, BB; Gruissem, W and Jones, RL. 2000. Biochemistry and Molecular Biology of Plants. American Society of Plant Physiologists. Maryland, USA.

·         Powar,C.B. Cell Biology. Himalaya Publishing House, Mumbai.

Introductory Cell Biology. Veer Bala Rastogi

References: 
  • De Robertis. Cell and Molecular Biology. Waverly International.
  • Gardener, M.J.Simmons, D.P.Snustad.  Principles of Genetics, 8th Edition.JohnWiley and Sons, Singapore
  • Karp and Gerald. Cell and Molecular Biology: Concepts and Experiments (3rd edition). John Wiley & Sons.
  • Kleinsmith, LJ and Kish, VM. 1995. Principles of Cell and Molecular Biology (2nd edition). Harper Collins College Publishers. New York, USA.
  • Krishnamurthy, KV. 2000. Methods in Cell Wall Cytochemistry. CRC Press,Boca Raton; Florida.
  • Lewin, B 2000. Genes VII. Oxford University Press, New York.
  • Lodish, H; Berk, A; Zipursky, SL; Matsudiara, P; Baltimore, D and Darnell, J. 2000. Molecular Cell Biology (4th edition). WH Freeman & Co., New York.
  • Rost, T et al. 1998. Plant Biology. Wordsworth Publishing Co. California, USA.
  • Wolfe, SL. 1993. Molecular and Cellular Biology. Wordsworth Publishing Co. California, USA.
  • Weil, JH. 2003. Molecular Insight in Plant Biology. Oxford & IBH Publishing Co. Pvt. Ltd.

 

Academic Year: